TECBio Trainee, Jenea Adams, to present TR&D1-supported work at two conferences

Ms. Jenea Adams, a visiting undergraduate student from the University of Dayton worked with Ivet Bahar and her team this summer using ProDy to investigate the characteristics of binding and allosteric sites in proteins.  In her 10-week project, Jenea used Anisotropic Network Modeling (ANM), perturbation response scanning, and statistical and conformational analyses on 768 protein complexes from the PDB to look for correlations of residue identities as sensors or effectors with their locations within the three dimensional protein structures.  She found that sensor residues have a higher propensity to reside at protein-protein interfaces than their effector counterparts.  Her results have implications for additional insights into more effective drug design and the mechanisms of allostery.  Jenea’s work was selected for presentations at two conferences – the Research Experiences for Undergraduates (REU) Symposium in Arlington, VA (https://www.cur.org/what/events/students/reu/) and the Annual Biomedical Research Conference for Minority Students (ABRCMS;  http://www.abrcms.org/).  

2018 TECBio Summer REU Program Students

Top (left to right): Gabrielle LaRosa, Dominique Cantave, Gabrielle Coffing, Naina Balepur, Jenea Adams, Jason Dennis, Alex Ludwig, Tom Dougherty. Bottom: Lauren Petrina, Olivia Campos, Joseph Monaco, Caleb Reagor, Gabriella Gerlach, Jack Zhao.